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- B311d3b94cb4db24f1c3e4e14c948827a NCIT_P378 "NCI" @default.
- B311d3b94cb4db24f1c3e4e14c948827a type Axiom @default.
- B311d3b94cb4db24f1c3e4e14c948827a annotatedProperty IAO_0000115 @default.
- B311d3b94cb4db24f1c3e4e14c948827a annotatedSource NCIT_C61917 @default.
- B311d3b94cb4db24f1c3e4e14c948827a annotatedTarget "A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors." @default.