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- B3135dd1a37a617de17b69e81b97385b4 NCIT_P378 "NCI" @default.
- B3135dd1a37a617de17b69e81b97385b4 type Axiom @default.
- B3135dd1a37a617de17b69e81b97385b4 annotatedProperty IAO_0000115 @default.
- B3135dd1a37a617de17b69e81b97385b4 annotatedSource NCIT_C2485 @default.
- B3135dd1a37a617de17b69e81b97385b4 annotatedTarget "A vaccine comprise of a canarypox viral vector that carries the gene for human B7.1 (CD80 antigen) with potential use as an autologous therapeutic cancer vaccine. Tumor cells harvested from a patient are infected with ALVAC-hB7 1, thereby producing an autologous cell line that exhibits increased expression of HLA class I and class II, CD54 (ICAM), and CD80. Increased expression of these proteins by this autologous cell line may activate an antitumor T-cell response when the modified cells are administered to the patient. (NCI04)" @default.