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- B313f4b65fc673778e9ce5a63cfc07b75 NCIT_P378 "NCI" @default.
- B313f4b65fc673778e9ce5a63cfc07b75 type Axiom @default.
- B313f4b65fc673778e9ce5a63cfc07b75 annotatedProperty IAO_0000115 @default.
- B313f4b65fc673778e9ce5a63cfc07b75 annotatedSource NCIT_C79831 @default.
- B313f4b65fc673778e9ce5a63cfc07b75 annotatedTarget "The orally bioavailable mesylate salt of masatinib, a multi-targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild-type and mutated forms of the stem cell factor receptor (c-Kit; SCFR); platelet-derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor cell proliferation may be inhibited in cancer cell types that overexpress these receptor tyrosine kinases (RTKs)." @default.