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- B31d6490a5e069d7d0c0ee1cb7eede095 NCIT_P378 "NCI" @default.
- B31d6490a5e069d7d0c0ee1cb7eede095 type Axiom @default.
- B31d6490a5e069d7d0c0ee1cb7eede095 annotatedProperty IAO_0000115 @default.
- B31d6490a5e069d7d0c0ee1cb7eede095 annotatedSource NCIT_C81627 @default.
- B31d6490a5e069d7d0c0ee1cb7eede095 annotatedTarget "The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction." @default.