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- B324ef9d649eb6a5e5521045882bb6e3b NCIT_P378 "NCI" @default.
- B324ef9d649eb6a5e5521045882bb6e3b type Axiom @default.
- B324ef9d649eb6a5e5521045882bb6e3b annotatedProperty IAO_0000115 @default.
- B324ef9d649eb6a5e5521045882bb6e3b annotatedSource NCIT_C21588 @default.
- B324ef9d649eb6a5e5521045882bb6e3b annotatedTarget "The type of ubiquitin modification determines the functional consequences for the modified protein. Monoubiquitination does not serve as a proteasome targeting signal, but plays other distinct roles. Target proteins are monoubiquitinated on one or more lysine residues, which serve as a signal for intracellular sorting as well as endocytosis of cell-surface proteins. Monoubiquitination of cell-surface receptors serves as a signal to target them to lysosome, where they are degraded by lysosomal proteases. (From PMID and NCI)" @default.