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- B3332323b34c75ff9373982d81715b433 NCIT_P378 "NCI" @default.
- B3332323b34c75ff9373982d81715b433 type Axiom @default.
- B3332323b34c75ff9373982d81715b433 annotatedProperty IAO_0000115 @default.
- B3332323b34c75ff9373982d81715b433 annotatedSource NCIT_C1070 @default.
- B3332323b34c75ff9373982d81715b433 annotatedTarget "A synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. Although less prone to glutathione inactivation compared to cisplatin, resistance to this agent has been observed in vitro due to repair of platination damage by tumor cells. (NCI04)" @default.