Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B33a0b0b6be1f4d1a1b8a3bdf27e56c9d> ?p ?o ?g. }
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- B33a0b0b6be1f4d1a1b8a3bdf27e56c9d NCIT_P378 "NCI" @default.
- B33a0b0b6be1f4d1a1b8a3bdf27e56c9d type Axiom @default.
- B33a0b0b6be1f4d1a1b8a3bdf27e56c9d annotatedProperty IAO_0000115 @default.
- B33a0b0b6be1f4d1a1b8a3bdf27e56c9d annotatedSource NCIT_C81036 @default.
- B33a0b0b6be1f4d1a1b8a3bdf27e56c9d annotatedTarget "A semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiofur binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.