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- B34576fd98d7cb226e48b558bd82c3efa NCIT_P378 "NCI" @default.
- B34576fd98d7cb226e48b558bd82c3efa type Axiom @default.
- B34576fd98d7cb226e48b558bd82c3efa annotatedProperty IAO_0000115 @default.
- B34576fd98d7cb226e48b558bd82c3efa annotatedSource NCIT_C48186 @default.
- B34576fd98d7cb226e48b558bd82c3efa annotatedTarget "This process is initiated by the formation of heterochromatin which ultimately leads to transcriptional inactivation or silencing. Once formed, heterochromatin can be inherited through many cell divisions, including meiosis. Inappropriate gain of heterochromatin structure, such as the inactivation of tumor suppressor genes by DNA hyper-methylation at their promoter regions, can be directly linked to carcinogenesis." @default.