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- B35062a0d6795662b253ad99e116959a4 NCIT_P378 "NCI" @default.
- B35062a0d6795662b253ad99e116959a4 type Axiom @default.
- B35062a0d6795662b253ad99e116959a4 annotatedProperty IAO_0000115 @default.
- B35062a0d6795662b253ad99e116959a4 annotatedSource NCIT_C70618 @default.
- B35062a0d6795662b253ad99e116959a4 annotatedTarget "Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components." @default.