Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B3663a4fe61f3b950bd3dc6224f34cad2> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B3663a4fe61f3b950bd3dc6224f34cad2 NCIT_P378 "BIOCARTA" @default.
- B3663a4fe61f3b950bd3dc6224f34cad2 type Axiom @default.
- B3663a4fe61f3b950bd3dc6224f34cad2 annotatedProperty NCIT_P325 @default.
- B3663a4fe61f3b950bd3dc6224f34cad2 annotatedSource NCIT_C39001 @default.
- B3663a4fe61f3b950bd3dc6224f34cad2 annotatedTarget "The binding of b-arrestins to agonist-occupied GPCRs coincides with the recruitment of Src family tyrosine kinases, including c-Src, Hck and c-Fgr (Src-TK), to the receptor-b-arrestin complex. Several signaling events have been reported to involve b-arrestin-dependent Src recruitment. These include the regulation of clathrin-dependent beta2-adrenergic receptor endocytosis by tyrosine phosphorylation of dynamin, Ras-dependent activation of the ERK1/2 MAP kinase cascade and stimulation of cell proliferation by beta2-adrenergic and neurokinin NK1 receptors, and stimulation of chemokine CXCR1 receptor-mediated neutrophil degranulation. (This definition may be outdated - see the DesignNote.)" @default.