Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B3711b73c3dd8f52580b8ff18954c63f7> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B3711b73c3dd8f52580b8ff18954c63f7 NCIT_P378 "NCI" @default.
- B3711b73c3dd8f52580b8ff18954c63f7 type Axiom @default.
- B3711b73c3dd8f52580b8ff18954c63f7 annotatedProperty IAO_0000115 @default.
- B3711b73c3dd8f52580b8ff18954c63f7 annotatedSource NCIT_C26561 @default.
- B3711b73c3dd8f52580b8ff18954c63f7 annotatedTarget "The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus. Two of the enzymes that are part of this machinery are DNA polymerase alpha (POLA), the principal replication enzyme, and primase, the enzyme that catalyzes the synthesis of oligoribonucleotide primers on a DNA template; the primers are required by DNA polymerase alpha to initiate DNA synthesis. These 2 proteins form an enzymatic complex Primase, in turn, is a complex of two proteins, a 49kDa subunit and a 58kDa subunit. Mutation of the 58kDa subunit suggests that it is important for initiation, elongation, and counting. (from OMIM and Biochemistry 2002;41:4891-900)" @default.