Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B38fd309a3d4a7eef514a91eb43b6e366> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B38fd309a3d4a7eef514a91eb43b6e366 NCIT_P378 "NCI" @default.
- B38fd309a3d4a7eef514a91eb43b6e366 type Axiom @default.
- B38fd309a3d4a7eef514a91eb43b6e366 annotatedProperty IAO_0000115 @default.
- B38fd309a3d4a7eef514a91eb43b6e366 annotatedSource NCIT_C508 @default.
- B38fd309a3d4a7eef514a91eb43b6e366 annotatedTarget "A derivative of propionic acid, and a phenylalkanoic acid derivative of non-steroidal antiinflammatory drugs (NSAIDs) with analgesic, antiinflammatory and antipyretic effects. Flurbiprofen non-selectively binds to and inhibits cyclooxygenase (COX). This results in a reduction of arachidonic acid conversion into prostaglandins that are involved in the regulation of pain, inflammation and fever. This NSAID also inhibits carbonic anhydrase, thereby reducing the production of hydrogen and bicarbonate ions. Upon ocular administration, flurbiprofen may reduce bicarbonate ion concentrations leading to a decrease in the production of aqueous humor, thereby lowering intraocular pressure." @default.