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- B3a85fc6efe99f1ee6a224e5bf9299a43 NCIT_P378 "NCI" @default.
- B3a85fc6efe99f1ee6a224e5bf9299a43 type Axiom @default.
- B3a85fc6efe99f1ee6a224e5bf9299a43 annotatedProperty IAO_0000115 @default.
- B3a85fc6efe99f1ee6a224e5bf9299a43 annotatedSource NCIT_C2601 @default.
- B3a85fc6efe99f1ee6a224e5bf9299a43 annotatedTarget "A radioconjugate consisting of the octreotide derivative edotreotide labeled with yttrium 90 (Y-90) with potential radiotherapeutic uses. Similar to octreotide, yttrium Y 90-edotreotide binds to somatostatin receptors (SSTRs), especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells, delivering tissue-specific, beta-emitting nuclide Y-90-mediated cytotoxicity to SSTR-positive cells. Yttrium Y 90-edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of the somatostatin analogue octreotide and chelating the substituted octreotide to Y-90 via dodecanetetraacetic acid (DOTA)." @default.