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- B3cb1e4038f1a426579783660d0e0001b NCIT_P378 "NCI" @default.
- B3cb1e4038f1a426579783660d0e0001b type Axiom @default.
- B3cb1e4038f1a426579783660d0e0001b annotatedProperty IAO_0000115 @default.
- B3cb1e4038f1a426579783660d0e0001b annotatedSource NCIT_C665 @default.
- B3cb1e4038f1a426579783660d0e0001b annotatedTarget "The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin." @default.