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- B3d2c9ad4c4173fc549b2376443ed641a NCIT_P378 "NCI" @default.
- B3d2c9ad4c4173fc549b2376443ed641a type Axiom @default.
- B3d2c9ad4c4173fc549b2376443ed641a annotatedProperty IAO_0000115 @default.
- B3d2c9ad4c4173fc549b2376443ed641a annotatedSource NCIT_C73269 @default.
- B3d2c9ad4c4173fc549b2376443ed641a annotatedTarget "A low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagonist." @default.