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- B3d92b57572d19390e46eab073190da64 NCIT_P378 "NCI" @default.
- B3d92b57572d19390e46eab073190da64 type Axiom @default.
- B3d92b57572d19390e46eab073190da64 annotatedProperty IAO_0000115 @default.
- B3d92b57572d19390e46eab073190da64 annotatedSource NCIT_C71622 @default.
- B3d92b57572d19390e46eab073190da64 annotatedTarget "An indolinone derivative and tyrosine kinase inhibitor with potential antineoplastic activity. Sunitinib blocks the tyrosine kinase activities of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor b (PDGFRb), and c-kit, thereby inhibiting angiogenesis and cell proliferation. This agent also inhibits the phosphorylation of Fms-related tyrosine kinase 3 (FLT3), another receptor tyrosine kinase expressed by some leukemic cells." @default.