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- B3ded98b356f431c85b98b9b90784dad0 NCIT_P378 "NCI" @default.
- B3ded98b356f431c85b98b9b90784dad0 type Axiom @default.
- B3ded98b356f431c85b98b9b90784dad0 annotatedProperty IAO_0000115 @default.
- B3ded98b356f431c85b98b9b90784dad0 annotatedSource NCIT_C102782 @default.
- B3ded98b356f431c85b98b9b90784dad0 annotatedTarget "A cancer vaccine containing autologous dendritic cells pulsed with a fusion product of an epitope of human tumor-associated epithelial mucin 1 (MUC1) antigen and the vaccine adjuvant mannan (oxidized mannose), with potential antineoplastic activity. When the modified dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in tumor cell lysis. Addition of manna in this vaccine, enhances immune recognition. MUC1 antigen, a high-molecular-weight transmembrane glycoprotein, is overexpressed on many tumor cells." @default.