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- B3ff6ee6a08b83ce0b47063551f5f22c2 NCIT_P378 "NCI" @default.
- B3ff6ee6a08b83ce0b47063551f5f22c2 type Axiom @default.
- B3ff6ee6a08b83ce0b47063551f5f22c2 annotatedProperty IAO_0000115 @default.
- B3ff6ee6a08b83ce0b47063551f5f22c2 annotatedSource NCIT_C2015 @default.
- B3ff6ee6a08b83ce0b47063551f5f22c2 annotatedTarget "A synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth." @default.