Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B425d29594843cac4de5506e422046936> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B425d29594843cac4de5506e422046936 NCIT_P378 "NCI" @default.
- B425d29594843cac4de5506e422046936 type Axiom @default.
- B425d29594843cac4de5506e422046936 annotatedProperty IAO_0000115 @default.
- B425d29594843cac4de5506e422046936 annotatedSource NCIT_C151936 @default.
- B425d29594843cac4de5506e422046936 annotatedTarget "A preparation of human autologous peripheral blood lymphocytes (PBLs) that have been genetically engineered to express a T-cell receptor (TCR) that specifically targets the viral oncoprotein human papillomavirus type 16 (HPV-16) E6, with potential antineoplastic activity. Upon administration, the HPV E6 TCR genetically-modified T-cells target and bind to HPV-16 E6-expressing tumor cells, which leads to specific cytotoxic T-lymphocyte (CTL)-mediated killing of HPV-16 E6-positive tumor cells. HPV-16 E6, a cell surface glycoprotein, plays a key role in the tumorigenesis of various HPV-associated tumors and is absent from healthy human tissues." @default.