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- B42776851272d109daef47f33d144e1e0 NCIT_P378 "NCI" @default.
- B42776851272d109daef47f33d144e1e0 type Axiom @default.
- B42776851272d109daef47f33d144e1e0 annotatedProperty IAO_0000115 @default.
- B42776851272d109daef47f33d144e1e0 annotatedSource NCIT_C156698 @default.
- B42776851272d109daef47f33d144e1e0 annotatedTarget "A synthetic compound containing the bisphosphonate etidronate (hydroxyethylidene diphosphonate, HEDP) labeled with rhenium Re188, a beta-emitting radioisotope with potential antineoplastic activity. Upon administration, Re-188 etidronate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. The beta-radiation may provide localized anti-tumor radiotoxicity while sparing extramedullary bone marrow tissues." @default.