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- B431945b94a0495c64931f2c64672e8bf NCIT_P378 "NCI" @default.
- B431945b94a0495c64931f2c64672e8bf type Axiom @default.
- B431945b94a0495c64931f2c64672e8bf annotatedProperty IAO_0000115 @default.
- B431945b94a0495c64931f2c64672e8bf annotatedSource NCIT_C971 @default.
- B431945b94a0495c64931f2c64672e8bf annotatedTarget "An iodinated doxorubicin analogue with antiamyloid activity. 4'-Iodo-4'-deoxydoxorubicin (IDOX) binds with high affinity to five types of natural amyloid fibrils including immunoglobulin light chains, amyloid A, transthyretin (methionine-30 variant), beta-protein (Alzheimer), and beta2-microglobulin. This agent may inhibit fibril growth, increasing the solubility of amyloid tissue deposits and facilitating their clearance. IDOX has also been shown to insulin amyloid fibrillogenesis in vitro." @default.