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- B451e1dcbd76112c1dc881121394a1af2 NCIT_P378 "NCI" @default.
- B451e1dcbd76112c1dc881121394a1af2 type Axiom @default.
- B451e1dcbd76112c1dc881121394a1af2 annotatedProperty IAO_0000115 @default.
- B451e1dcbd76112c1dc881121394a1af2 annotatedSource NCIT_C180526 @default.
- B451e1dcbd76112c1dc881121394a1af2 annotatedTarget "The besylate salt form of clifutinib, an orally bioavailable, selective, small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2), with potential antineoplastic activity. Upon oral administration, clifutinib targets, binds to and inhibits the activity of FLT3. This inhibits the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias." @default.