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- B46347dae4eb1bc7f71ca4eef83175a68 NCIT_P378 "NCI" @default.
- B46347dae4eb1bc7f71ca4eef83175a68 type Axiom @default.
- B46347dae4eb1bc7f71ca4eef83175a68 annotatedProperty IAO_0000115 @default.
- B46347dae4eb1bc7f71ca4eef83175a68 annotatedSource NCIT_C65329 @default.
- B46347dae4eb1bc7f71ca4eef83175a68 annotatedTarget "The sodium salt form of cilastatin, a renal dehydropeptidase inhibitor, that can be used to inhibit the activity of renal dehydropeptidase. Upon administration of cilastatin sodium, cilastatin targets, binds to and inhibits the activity of renal dehydropeptidase. This reduces the breakdown of drugs, such as the broad spectrum beta-lactam carbapenem imipenem, by renal dehydropeptidase, and thereby increases the activity and therapeutic effect of such drugs that would otherwise be metabolized by renal dehydropeptidase." @default.