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- B46a6e5838df335d016854698543e3ab1 NCIT_P378 "NCI" @default.
- B46a6e5838df335d016854698543e3ab1 type Axiom @default.
- B46a6e5838df335d016854698543e3ab1 annotatedProperty IAO_0000115 @default.
- B46a6e5838df335d016854698543e3ab1 annotatedSource NCIT_C201132 @default.
- B46a6e5838df335d016854698543e3ab1 annotatedTarget "A preparation of autologous T-lymphocytes that are engineered to express a T-cell receptor (TCR) specific for melanoma-associated antigen A1 (MAGE-A1) presented on human leukocyte antigen (HLA)-C*07:02, with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702 specifically recognize and bind to MAGE-A1 expressed on tumor cells. This may lead to cytotoxic T-lymphocyte (CTL)-mediated elimination of tumor cells expressing MAGE-A1. MAGE-A1 is a tumor-associated antigen (TAA) overexpressed by a variety of cancer cell types." @default.