Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B46ec4bca9f19af0a45cdaf70ff316f41> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B46ec4bca9f19af0a45cdaf70ff316f41 NCIT_P378 "NCI" @default.
- B46ec4bca9f19af0a45cdaf70ff316f41 type Axiom @default.
- B46ec4bca9f19af0a45cdaf70ff316f41 annotatedProperty IAO_0000115 @default.
- B46ec4bca9f19af0a45cdaf70ff316f41 annotatedSource NCIT_C76034 @default.
- B46ec4bca9f19af0a45cdaf70ff316f41 annotatedTarget "A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefluprenam binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.