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- B4762eadd81f3d089f7dca5422e9a0f39 NCIT_P378 "NCI" @default.
- B4762eadd81f3d089f7dca5422e9a0f39 type Axiom @default.
- B4762eadd81f3d089f7dca5422e9a0f39 annotatedProperty IAO_0000115 @default.
- B4762eadd81f3d089f7dca5422e9a0f39 annotatedSource NCIT_C102877 @default.
- B4762eadd81f3d089f7dca5422e9a0f39 annotatedTarget "A fully human monoclonal antibody targeting the vascular endothelial growth factor receptor 2 (VEGFR2), with potential antiangiogenic activity. Upon administration, olinvacimab specifically binds to VEGFR2, thereby preventing the binding of its ligand VEGF. This may result in the inhibition of tumor angiogenesis and a decrease in tumor nutrient supply. VEGFR2 is a pro-angiogenic growth factor receptor tyrosine kinase expressed by endothelial cells, while VEGF is overexpressed in many tumors and is correlated to tumor progression." @default.