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- B47681ae3b0e894bd6f9f14cf928c8ab8 NCIT_P378 "NCI" @default.
- B47681ae3b0e894bd6f9f14cf928c8ab8 type Axiom @default.
- B47681ae3b0e894bd6f9f14cf928c8ab8 annotatedProperty IAO_0000115 @default.
- B47681ae3b0e894bd6f9f14cf928c8ab8 annotatedSource NCIT_C102747 @default.
- B47681ae3b0e894bd6f9f14cf928c8ab8 annotatedTarget "A derivative of pyridoxyl ethyldiamine (PLED) and mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with antioxidant, metal chelating and potential chemoprotective activities. Upon administration, PLED-based MnSOD mimetic mimics MnSOD and scavenges oxygen free radicals such as superoxide anion, hydrogen peroxide, and hydroxyl radical, thereby preventing oxygen free radical damage to macromolecules such as DNA and minimizing oxygen free radical-related chemotoxicity in normal tissues. In addition, this agent is able to strongly bind to iron." @default.