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- B47e415491334ee6ce68c025a1862d92f NCIT_P378 "NCI" @default.
- B47e415491334ee6ce68c025a1862d92f type Axiom @default.
- B47e415491334ee6ce68c025a1862d92f annotatedProperty IAO_0000115 @default.
- B47e415491334ee6ce68c025a1862d92f annotatedSource NCIT_C19419 @default.
- B47e415491334ee6ce68c025a1862d92f annotatedTarget "Exposure to DNA-damaging agents and subsequent energy expenditures by a cell to repair DNA damage. Genotoxic stress elicits biochemical responses that either enhance cell survival or lead to cell death. These biochemical responses include DNA-damage-inducible repair and increasing expression of a variety of proteins by both transcriptional and post-transcriptional mechanisms. Genotoxic stresses frequently activate signal transduction pathways that originate in the cell membrane or cytoplasm, triggering similar phosphorylation cascades to those induced by the activation of cell-surface receptors." @default.