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- B49d93ef2fb3efa472a464dbc8dae6268 NCIT_P378 "NCI" @default.
- B49d93ef2fb3efa472a464dbc8dae6268 type Axiom @default.
- B49d93ef2fb3efa472a464dbc8dae6268 annotatedProperty IAO_0000115 @default.
- B49d93ef2fb3efa472a464dbc8dae6268 annotatedSource NCIT_C47425 @default.
- B49d93ef2fb3efa472a464dbc8dae6268 annotatedTarget "A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on the GABA receptor. This leads to an increase in the duration of GABA-mediated opening of chloride channels and enhances the inhibitory effect of GABA. Consequently, its physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory depression and the drug causes tolerance and dependence." @default.