Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B4a041e545653453ee81a5739f275671c> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B4a041e545653453ee81a5739f275671c NCIT_P378 "NCI" @default.
- B4a041e545653453ee81a5739f275671c type Axiom @default.
- B4a041e545653453ee81a5739f275671c annotatedProperty IAO_0000115 @default.
- B4a041e545653453ee81a5739f275671c annotatedSource NCIT_C52184 @default.
- B4a041e545653453ee81a5739f275671c annotatedTarget "An orally bioavailable small molecule belonging to the azaspirane class of cationic amphiphilic agents with anti-inflammatory, antineoplastic, and antiangiogenic properties. Atiprimod inhibits the phosphorylation of signal transducer and activator of transcription 3 (STAT3), blocking the signalling pathways of interleukin-6 and vascular endothelial growth factor (VEGF) and downregulating the anti-apoptotic proteins Bcl-2, Bcl-XL, and Mcl-1, thereby inhibiting cell proliferation, inducing cell cycle arrest, and inducing apoptosis." @default.