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- B4bf30973b7d079066faad5f203718cc4 NCIT_P378 "NCI" @default.
- B4bf30973b7d079066faad5f203718cc4 type Axiom @default.
- B4bf30973b7d079066faad5f203718cc4 annotatedProperty IAO_0000115 @default.
- B4bf30973b7d079066faad5f203718cc4 annotatedSource NCIT_C657 @default.
- B4bf30973b7d079066faad5f203718cc4 annotatedTarget "A nitroimidazole with radiosensitizing and antineoplastic properties. Exhibiting high electron affinity, misonidazole induces the formation of free radicals and depletes radioprotective thiols, thereby sensitizing hypoxic cells to the cytotoxic effects of ionizing radiation. This single-strand breaks in DNA induced by this agent result in the inhibition of DNA synthesis. (NCI04)" @default.