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- B4dfdad21ecf331317a49eaf4c5d9f520 NCIT_P378 "NCI" @default.
- B4dfdad21ecf331317a49eaf4c5d9f520 type Axiom @default.
- B4dfdad21ecf331317a49eaf4c5d9f520 annotatedProperty IAO_0000115 @default.
- B4dfdad21ecf331317a49eaf4c5d9f520 annotatedSource NCIT_C48383 @default.
- B4dfdad21ecf331317a49eaf4c5d9f520 annotatedTarget "A cytokine-peptide conjugate composed of the cytokine tumor necrosis factor alpha (TNF-alpha) chemically linked to the peptide CNGRC. The peptide moiety CNGRC, a ligand for the membrane-bound metalloprotease CD13, binds to endothelial cells of the angiogenic vasculature that express CD13 (also known as aminopeptidase N); subsequently, the TNF-alpha moiety induces apoptosis in endothelial cells expressing CD13, thereby inhibiting tumor-associated angiogenesis. (NCI05)" @default.