Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B4e21c1cd87cca4c9effb0d9c2d0fc3a0> ?p ?o ?g. }
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- B4e21c1cd87cca4c9effb0d9c2d0fc3a0 NCIT_P378 "NCI" @default.
- B4e21c1cd87cca4c9effb0d9c2d0fc3a0 type Axiom @default.
- B4e21c1cd87cca4c9effb0d9c2d0fc3a0 annotatedProperty IAO_0000115 @default.
- B4e21c1cd87cca4c9effb0d9c2d0fc3a0 annotatedSource NCIT_C84846 @default.
- B4e21c1cd87cca4c9effb0d9c2d0fc3a0 annotatedTarget "A small-molecule pan-Aurora kinase inhibitor with potential antineoplastic activity. Aurora kinase inhibitor TTP607 selectively binds to and inhibits Aurora kinases A, B and C, which may result in the disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cellular division and proliferation in Aurora kinase-overexpressing tumor cells. Aurora kinases A, B and C, are serine/threonine kinases that play essential roles in mitotic checkpoint control and are overexpressed by a wide variety of tumor cell types." @default.