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- B4e9ea4e344805143beae38dbacb4677e NCIT_P378 "NCI" @default.
- B4e9ea4e344805143beae38dbacb4677e type Axiom @default.
- B4e9ea4e344805143beae38dbacb4677e annotatedProperty IAO_0000115 @default.
- B4e9ea4e344805143beae38dbacb4677e annotatedSource NCIT_C934 @default.
- B4e9ea4e344805143beae38dbacb4677e annotatedTarget "A synthetic derivative of vinblastine, a naturally occurring vinca alkaloid. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI04)" @default.