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- B4f5e0145100e0060137cbd3b7b6c1bdd NCIT_P378 "NCI" @default.
- B4f5e0145100e0060137cbd3b7b6c1bdd type Axiom @default.
- B4f5e0145100e0060137cbd3b7b6c1bdd annotatedProperty IAO_0000115 @default.
- B4f5e0145100e0060137cbd3b7b6c1bdd annotatedSource NCIT_C61665 @default.
- B4f5e0145100e0060137cbd3b7b6c1bdd annotatedTarget "A semisynthetic, broad-spectrum, second-generation cephalosporin with antibacterial activity. Cefoxitin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.