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- B52af0be15e9932b15c39f3fbd99b0424 NCIT_P378 "NCI" @default.
- B52af0be15e9932b15c39f3fbd99b0424 type Axiom @default.
- B52af0be15e9932b15c39f3fbd99b0424 annotatedProperty IAO_0000115 @default.
- B52af0be15e9932b15c39f3fbd99b0424 annotatedSource NCIT_C179655 @default.
- B52af0be15e9932b15c39f3fbd99b0424 annotatedTarget "A fusion protein composed of fms-related tyrosine kinase 3 ligand (FLT3L) and agonist fused to an immunoglobulin (Ig) fragment crystallizable region (Fc region), with potential immunostimulating activity. Upon administration of the FLT3 agonist-Fc fusion protein GS-3583, the FLT3 agonist moiety specifically targets, binds to, and activates FLT3 and, synergistically with other growth factors, stimulates the proliferation and mobilization of bone marrow precursor cells, including CD34+ cells, and dendritic cells (DCs). FLT3 agonist-Fc fusion protein GS-3583 has a longer serum half-life compared with soluble FLT3L." @default.