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- B535ea586123c2858f2735969f36da6f6 NCIT_P378 "NCI" @default.
- B535ea586123c2858f2735969f36da6f6 type Axiom @default.
- B535ea586123c2858f2735969f36da6f6 annotatedProperty IAO_0000115 @default.
- B535ea586123c2858f2735969f36da6f6 annotatedSource NCIT_C47957 @default.
- B535ea586123c2858f2735969f36da6f6 annotatedTarget "The sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction." @default.