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- B53712461e8a45836d125d0733d30a07e NCIT_P378 "NCI" @default.
- B53712461e8a45836d125d0733d30a07e type Axiom @default.
- B53712461e8a45836d125d0733d30a07e annotatedProperty IAO_0000115 @default.
- B53712461e8a45836d125d0733d30a07e annotatedSource NCIT_C80867 @default.
- B53712461e8a45836d125d0733d30a07e annotatedTarget "An orally bioavailable indole ether quinazoline derivative and vascular endothelial growth factor receptor (VEGFR) inhibitor, with potential antineoplastic activity. Upon oral administration, cediranib binds to and inhibits the three VEGFR subtypes 1 (VEGFR-1), 2 (VEGFR-2) and 3 (VEGFR-3), thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth. Expression of VEGFRs may be upregulated in a variety of tumor cell types." @default.