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- B53bdbf3343b9d130ed01bf8750d80f2c NCIT_P378 "NCI" @default.
- B53bdbf3343b9d130ed01bf8750d80f2c type Axiom @default.
- B53bdbf3343b9d130ed01bf8750d80f2c annotatedProperty IAO_0000115 @default.
- B53bdbf3343b9d130ed01bf8750d80f2c annotatedSource NCIT_C80327 @default.
- B53bdbf3343b9d130ed01bf8750d80f2c annotatedTarget "The hydrochloride salt of a saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), safingol competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo." @default.