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- B54d6665063e654d896799dc3dea24fa9 NCIT_P378 "NCI" @default.
- B54d6665063e654d896799dc3dea24fa9 type Axiom @default.
- B54d6665063e654d896799dc3dea24fa9 annotatedProperty IAO_0000115 @default.
- B54d6665063e654d896799dc3dea24fa9 annotatedSource NCIT_C2844 @default.
- B54d6665063e654d896799dc3dea24fa9 annotatedTarget "A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Actinomycin F1 intercalates into the minor groove of DNA and binds to topoisomerase II, leading to the inhibition of DNA replication and RNA and protein synthesis. (NCI04)" @default.