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- B555dc7beab7e2fda0436f126aa072b78 NCIT_P378 "NCI" @default.
- B555dc7beab7e2fda0436f126aa072b78 type Axiom @default.
- B555dc7beab7e2fda0436f126aa072b78 annotatedProperty IAO_0000115 @default.
- B555dc7beab7e2fda0436f126aa072b78 annotatedSource NCIT_C187300 @default.
- B555dc7beab7e2fda0436f126aa072b78 annotatedTarget "A preparation of T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19 CAR T cells AT101 recognize and bind to CD19-expressing tumor cells, thereby inducing selective toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies." @default.