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- B558ffb2211045b2174c7ae8e79fbd679 NCIT_P378 "NCI" @default.
- B558ffb2211045b2174c7ae8e79fbd679 type Axiom @default.
- B558ffb2211045b2174c7ae8e79fbd679 annotatedProperty IAO_0000115 @default.
- B558ffb2211045b2174c7ae8e79fbd679 annotatedSource NCIT_C61877 @default.
- B558ffb2211045b2174c7ae8e79fbd679 annotatedTarget "The sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production." @default.