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- B55b0712d05ce038b11d7de1c10395fcc NCIT_P378 "NCI" @default.
- B55b0712d05ce038b11d7de1c10395fcc type Axiom @default.
- B55b0712d05ce038b11d7de1c10395fcc annotatedProperty IAO_0000115 @default.
- B55b0712d05ce038b11d7de1c10395fcc annotatedSource NCIT_C716 @default.
- B55b0712d05ce038b11d7de1c10395fcc annotatedTarget "A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors." @default.