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- B56b49781250d42f28d15c63015ceec67 NCIT_P378 "NCI" @default.
- B56b49781250d42f28d15c63015ceec67 type Axiom @default.
- B56b49781250d42f28d15c63015ceec67 annotatedProperty IAO_0000115 @default.
- B56b49781250d42f28d15c63015ceec67 annotatedSource NCIT_C91736 @default.
- B56b49781250d42f28d15c63015ceec67 annotatedTarget "A liposomal formulation containing the antisense oligodeoxynucleotide (ODN) growth factor receptor-bound protein 2 (Grb2), with potential antineoplastic activity. Upon administration, liposome-incorporated Grb2 antisense oligodeoxynucleotide binds directly to and blocks Grb2 mRNA, thereby preventing Grb2 protein synthesis, leading to inhibition of cell proliferation of cancer cells overexpressing Grb2. Grb2, an adaptor protein involved in growth signaling pathways, is upregulated in certain tumor cells." @default.