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- B57773ffbf9b988c9a9ce4c4e57f11cbe NCIT_P378 "NCI" @default.
- B57773ffbf9b988c9a9ce4c4e57f11cbe type Axiom @default.
- B57773ffbf9b988c9a9ce4c4e57f11cbe annotatedProperty IAO_0000115 @default.
- B57773ffbf9b988c9a9ce4c4e57f11cbe annotatedSource NCIT_C2688 @default.
- B57773ffbf9b988c9a9ce4c4e57f11cbe annotatedTarget "A Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with antineoplastic activity. Paclitaxel binds to and stabilizes microtubules, preventing their depolymerization and so inhibiting cellular motility, mitosis, and replication. This formulation solubilizes paclitaxel without the use of the solvent Cremophor, thereby permitting the administration of larger doses of paclitaxel while avoiding the toxic effects associated with Cremophor." @default.