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- B57b0408c29f2bf0a74af1f8fad63f344 NCIT_P378 "NCI" @default.
- B57b0408c29f2bf0a74af1f8fad63f344 type Axiom @default.
- B57b0408c29f2bf0a74af1f8fad63f344 annotatedProperty IAO_0000115 @default.
- B57b0408c29f2bf0a74af1f8fad63f344 annotatedSource NCIT_C101368 @default.
- B57b0408c29f2bf0a74af1f8fad63f344 annotatedTarget "An antisense oligonucleotide targeting signal transducer and activator of transcription 3 (STAT3) with potential antitumor activity. Danvatirsen binds to STAT3 mRNA, thereby inhibiting translation of the transcript. Suppression of STAT3 expression induces tumor cell apoptosis and decreases tumor cell growth. STAT3, a protein overexpressed in a variety of human cancers, plays a critical role in tumor cell growth and survival." @default.