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- B5835ee99b3ea4f9ab1f13ae33f7f2ce7 NCIT_P378 "BIOCARTA" @default.
- B5835ee99b3ea4f9ab1f13ae33f7f2ce7 type Axiom @default.
- B5835ee99b3ea4f9ab1f13ae33f7f2ce7 annotatedProperty NCIT_P325 @default.
- B5835ee99b3ea4f9ab1f13ae33f7f2ce7 annotatedSource NCIT_C39211 @default.
- B5835ee99b3ea4f9ab1f13ae33f7f2ce7 annotatedTarget "Current data indicates that nuclear pore complex (NPC) RanBP2 (SUMO E3 ligase) protein sumoylates Mdm2 and HDAC proteins during nuclear translocation. A sumoylation-deficient HDAC showed reduced deacetylation activity and suggests that sumoylation may be an important regulatory mechanism for the control of transcriptional repression. (This definition may be outdated - see the DesignNote.)" @default.