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- B5a53280bb8da95a52315e69418f2afe4 NCIT_P378 "NCI" @default.
- B5a53280bb8da95a52315e69418f2afe4 type Axiom @default.
- B5a53280bb8da95a52315e69418f2afe4 annotatedProperty IAO_0000115 @default.
- B5a53280bb8da95a52315e69418f2afe4 annotatedSource NCIT_C102878 @default.
- B5a53280bb8da95a52315e69418f2afe4 annotatedTarget "The hydrochloride salt form of boanmycin (aka bleomycin A6), a component of the antibiotic bleomycin produced by Streptomyces species, with potential antineoplastic activity. Upon administration, boanmycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals. This causes single- and double-stranded DNA breaks which eventually leads to cell death. Compared to bleomycin, boanmycin appears to have a more favorable toxicity profile." @default.