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- B5a5ddc1dc27dd1c0e72ae2a3a8551071 NCIT_P378 "NCI" @default.
- B5a5ddc1dc27dd1c0e72ae2a3a8551071 type Axiom @default.
- B5a5ddc1dc27dd1c0e72ae2a3a8551071 annotatedProperty IAO_0000115 @default.
- B5a5ddc1dc27dd1c0e72ae2a3a8551071 annotatedSource NCIT_C1374 @default.
- B5a5ddc1dc27dd1c0e72ae2a3a8551071 annotatedTarget "A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. (NCI04)" @default.