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- B5b753771d0fb8a68f178279e0f21ae30 NCIT_P378 "NCI" @default.
- B5b753771d0fb8a68f178279e0f21ae30 type Axiom @default.
- B5b753771d0fb8a68f178279e0f21ae30 annotatedProperty IAO_0000115 @default.
- B5b753771d0fb8a68f178279e0f21ae30 annotatedSource NCIT_C49510 @default.
- B5b753771d0fb8a68f178279e0f21ae30 annotatedTarget "Human CDKN1C wild-type allele located in the vicinity of 11p15.5 and is approximately 2 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor 1C protein, plays a negative role in the regulation of cellular proliferation by inhibiting several G1 cyclin/Cdk complexes. Mutations of the gene, which generates variant alleles have been implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, suggesting that it is a tumor suppressor candidate." @default.